Certain GLP-1 therapies, including semaglutide (found in Ozempic, Rybelsus, and Wegovy), liraglutide (present in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound), have been linked to a possible increased risk of thyroid gland tumors, notably Medullary Thyroid Carcinoma (MTC), a type of thyroid cancer. This conclusion comes from animal studies where these GLP-1 medications led to tumor development in laboratory animals. However, it remains unconfirmed whether these medications pose the same risks to humans. For further details on the risks associated with semaglutide-containing medications approved by the FDA, you can find more information here.
It is crucial to inform your healthcare provider if you or any family member has a history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). In such cases, your doctor will likely advise against the use of GLP-1 medications due to these pre-existing risk factors.
If you are prescribed a GLP-1 medication and experience any of the following symptoms, it is important to contact your doctor immediately:
- A noticeable lump or swelling in your neck area
- Persistent hoarseness
- Difficulty swallowing
- Shortness of breath that is new or worsening
- Severe abdominal pain that does not subside
Before starting GLP-1 medications, ensure you have a comprehensive discussion with your healthcare provider about the following important aspects:
Allergies: Inform your doctor and pharmacist about any known allergies, particularly to semaglutide (including brand names Ozempic, Rybelsus, Wegovy) or similar GLP-1 medications like tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon BCise, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy), and lixisenatide (Adlyxin, or in Soliqua). Knowing your allergy history is a key part of Sesame Care in medication management, ensuring you avoid substances that could cause adverse reactions.
Personal and Family Medical History: It is vital to disclose if you have a personal or family history of medical conditions such as pancreatitis, diabetic retinopathy, gallbladder disease, or kidney disease. Also, inform your doctor about any recent episodes of diarrhea, nausea, vomiting, or an inability to drink fluids, as these can lead to dehydration and may be relevant when starting GLP-1 therapy. This detailed medical history is essential for personalized sesame care, allowing your doctor to assess your individual risk profile.
Current Medications and Supplements: Provide a complete list of all medications and supplements you are currently taking. This includes prescription and over-the-counter medicines, vitamins, nutritional supplements, and herbal products. This step is critical because GLP-1 medications can affect how your body absorbs other oral medications. Managing drug interactions is a critical aspect of sesame care, ensuring all treatments work safely and effectively together.
Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or currently breastfeeding. The use of GLP-1 medications during pregnancy and breastfeeding requires careful consideration and is an important part of sesame care for both mother and child.
Surgical Procedures: If you are scheduled for any surgery, including dental procedures, inform the medical or dental professional that you are currently taking a GLP-1 medication. This information is important for managing your sesame care perioperatively, as GLP-1 medications can have implications for anesthesia and surgical management.
It’s essential to have an in-depth conversation with your healthcare provider about these potential risks and to carefully consider your personal and family medical history when deciding whether GLP-1 medications are right for you. Your doctor can offer tailored advice and guidance based on your specific health situation, ensuring your sesame care is prioritized throughout your treatment journey.